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从50例患有重型地中海贫血、61例中度地中海贫血和41例镰形细胞地中海贫血患者(76例男性,76例女性,平均年龄为26.4±12.4岁)中收集血清。所有患者都接受过为期13.8±8.9年的输血治疗,剂量为21.3±17.1单位/年。33例患者曾患病毒性肝炎:10例与乙型肝炎病毒(HBV)有关,13例为非甲非乙型肝炎,10例病原不明确。对所有患者(152
Serum was collected from 50 patients with thalassemia major, 61 with thalassemia of the medium and 41 with sickle cell thalassemia (76 males, 76 females, mean age 26.4 ± 12.4 years). All patients received a blood transfusion of 13.8 ± 8.9 years at a dose of 21.3 ± 17.1 units / year. Thirty-three patients had viral hepatitis: 10 were associated with hepatitis B virus (HBV), 13 were non-A, non-B, and 10 were undefined. For all patients (152