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1990～1992年对48例新生儿缺氧缺血性脑病(HIE)做了头颅CT及耳廓微循环观察.结果,HIE患儿耳廓微循环的血管数较正常新生儿明显减少,细静脉明显扩张,流速显著减慢,差异非常显著.提示新生儿HIE有急性脑循环循障碍.其耳廓微循环障碍程度与CT所反映的脑损伤程度成正相关(r=0.313,P<0.05)。也与HIE的病情严重程度成正相关(r=0.512,P<0.01).表明脑微循环障碍在HIE发病机理中有重要作用.
From 1990 to 1992, 48 cases of neonatal hypoxic-ischemic encephalopathy (HIE) were examined by CT and microcirculation of the auricles.Results The number of blood vessels in the auricle microcirculation of HIE children was significantly decreased compared with normal neonates, Obviously expanding, and the velocity of blood flow significantly slowed down, the difference was very significant, which suggested that newborn infants with acute cerebral circulation disorder had a positive correlation with the extent of brain injury reflected by CT (r = 0.313, P <0.05). Also had a positive correlation with the severity of HIE (r = 0.512, P <0.01), indicating that cerebral microcirculation plays an important role in the pathogenesis of HIE.