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目的 :分析阿奇霉素在儿科临床应用中的不良反应及药学监护。方法 :选取医院2014年3月到2015年3月儿科所收治的220例患儿作为本次研究的对象,按照随机数字法分为实验组与观察组。实验组采用静脉注射阿奇霉素;常规组采用口服阿奇霉素。对比两组患儿不良反应的发生状况。结果 :两组患儿的不良反应主要包含过敏性休克、过敏性皮疹、发烧、胃肠不适。两组患儿的不良反应发生率无明显差异,不具备统计学意义(P>0.05)。结论 :阿奇霉素在儿科临床中用药会发生一定程度的不良反应,在用药时需要特别监护,规避不良反应的发生,提高临床用药价值。
Objective: To analyze the adverse reactions and pharmacological care of azithromycin in pediatric clinical application. Methods: A total of 220 children admitted to our hospital from March 2014 to March 2015 were selected as the subjects of this study and divided into experimental group and observation group according to random number method. The experimental group received intravenous azithromycin; the conventional group received oral azithromycin. The incidence of adverse reactions in both groups was compared. Results: Adverse reactions in two groups mainly included anaphylactic shock, allergic rash, fever, gastrointestinal discomfort. There was no significant difference in the incidence of adverse reactions between the two groups, with no statistical significance (P> 0.05). Conclusion: Azithromycin can cause some adverse reactions when used in pediatrics. Special care should be taken during the medication to avoid adverse reactions and increase the value of clinical medication.