Enhancement of the Pore Interconnectivity and Porosity of Calcium Phosphate Scaffolds by Acid-Etchin

来源 :Acta Metallurgica Sinica(English Letters) | 被引量 : 0次 | 上传用户:sil87sil
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Porous hydroxyapatite(HA)–tricalcium phosphate(TCP) ceramic scaffolds were prepared using a screw-type extrusion method with polymer beads. HA and dicalcium phosphate dehydrates(DCPD) were added at various ratios to obtain different HA/TCP ratios in sintered ceramic scaffolds. To further enhance the pore interconnectivity and porosity,the developed porous ceramic scaffolds were etched with acid solutions. The maximum porosity(~85%) was observed in the Ca-P scaffold with the lowest HA(~7%) content. On the other hand, the maximum compressive strength was noted in the scaffolds with the highest HA content(~85%). X-ray diffraction showed that the extent of the b-TCP to a-TCP phase transformation increased with decreasing HA/DCPD ratio. All HCl-etched scaffolds were observed to generate micropores,which improved the interconnectivity, while biomineralization was found to be the same for both the HCl-etched and nonetched scaffolds. In particular, hydrochloric acid etching is a promising method for improving the interconnectivity and porosity of the ceramic scaffolds. Porous hydroxyapatite (HA) -ctricalcium phosphate (TCP) ceramic scaffolds were prepared using a screw-type extrusion method with polymer beads. HA and dicalcium phosphate dehydrates (DCPD) were added at various ratios to obtain different HA / TCP ratios in sintered ceramic scaffolds The further porosity of the pore interconnectivity and porosity, the developed porous ceramic scaffolds were etched with acid solutions. The maximum porosity (~ 85%) was observed in the Ca-P scaffold with the lowest HA (~ 7%) content. other hand, the maximum compressive strength was noted in the scaffolds with the highest HA content (~ 85%). X-ray diffraction showed the extent of the b-TCP to a-TCP phase transformation increased with decreasing HA / DCPD ratio. All HCl-etched scaffolds were observed to generate micropores, which improved the interconnectivity, while biomineralization was found to be the same for both the HCl-etched and nonetched scaffolds. In particular, hydrochloric acid etching is a promising me thod for improving the interconnectivity and porosity of the ceramic scaffolds.
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