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目的：观察桃蛭枳朴合剂预防腹部术后肠粘连的临床疗效。方法：３９６例腹部手术患者随机分为防粘组１８８例和对照组２０８例，防粘组予桃蛭枳朴合剂口服或胃管中注入；对照组不予本合剂，余处理相同。观察两组首次肠鸣音恢复时间，首次排气排便时间，及用同位素Ｉ１３１胶囊示踪观察胃肠蠕动，用肠音描记仪描记肠鸣音频率、强度，２～３年后进行疗效随访。结果：防粘组肠鸣音恢复时间、首次排气排便时间明显早于对照组，Ｉ１３１胶囊在肠道中下移迅速、肠音描记频率快、波幅大，远期随访亦发现防粘组无粘率及总体疗效明显优于对照组（Ｐ＜００５）。结论：桃蛭枳朴合剂具有明显的促进术后胃肠蠕动，预防粘连发生的作用。
Objective: To observe the clinical efficacy of Taozhipu mixture in preventing postoperative abdominal adhesions. Methods: 396 patients undergoing abdominal surgery were randomly divided into two groups: 188 in the anti-adhesive group and 208 in the control group. The anti-adhesion group was given orally or injected into the stomach tube in the anti-adhesion group. The control group was not treated with the mixture and the remaining treatment was the same. Observed the first time of recovery of bowel sounds in the two groups, the first time of defecation, and gastrointestinal peristalsis with isotope I131 capsule tracing. The frequency and intensity of bowel sounds were recorded with a bowel toneograph. The follow-up effect was observed 2 to 3 years later. Results: In the anti-adhesion group, the recovery time of bowel sounds and the time of first flushing and defecation were significantly earlier than those of the control group. The I131 capsules rapidly moved down in the intestine, and the frequency and the amplitude of the vibrotomy were fast. The long-term follow-up also showed that the anti-adhesion group was not sticky. The rate and overall efficacy were significantly better than those in the control group (P < 0.05). Conclusion: Tao Zhi Pu He Decoction can obviously promote postoperative gastrointestinal motility and prevent the occurrence of adhesions.