论文部分内容阅读
目的 探讨癌症患者抑郁的诊断和盐酸氟西汀对其的疗效。方法 应用 Zung抑郁自评量表对 2 2 0例住院患者进行常规筛选 ,凡 Zung抑郁自评量表为抑郁状态者 ,再进行 Hamilton抑郁量表的检查。抗抑郁药 5 -羟色胺再摄取抑制剂 (SSRI)——盐酸氟西汀 (百优解 ) 2 0 m g/ d连续治疗 6周后 ,再进行上述量表评分及生活质量Karnofsky评分。结果 大部分患者的精神和躯体症状均有明显改善 ,抑郁自评量表评分明显下降 ,生活质量Karnofsky评分显著提高。结论 癌症与心理因素关系密切 ,癌症患者普遍存在抑郁情绪 ,用抗抑郁药治疗能显著改善症状 ,包括精神和躯体两方面的症状 ,并提高生活质量。抗抑郁药盐酸氟西汀疗效好 ,不良反应较小 ,耐受性较好。
Objective To investigate the diagnosis of depression in patients with cancer and the efficacy of fluoxetine hydrochloride. Methods A total of 220 inpatients were routinely screened using the Zung Self-rating Depression Scale. All patients with depression were assessed with the Depression Scale of Hamilton Depression Scale. Antidepressants 5 - serotonin reuptake inhibitors (SSRI) - fluoxetine hydrochloride (100 g solution) 2 0 m g / d continuous treatment for 6 weeks, then the above scale and quality of life Karnofsky score. Results The majority of patients had significant improvement in mental and physical symptoms. The scores of self-rating depression scale decreased significantly, and Karnofsky score of life quality increased significantly. Conclusions Cancer is closely related to psychological factors. Depression is commonly found in cancer patients. Treatment with antidepressants can significantly improve symptoms, including mental and physical symptoms, and improve quality of life. Antidepressant fluoxetine hydrochloride is effective, with less adverse reactions and better tolerability.