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目的:观察中医和西医治疗儿童哮喘(缓解期)的临床疗效。方法:将79例哮喘缓解期患儿随机均分为中医组及西医组。中医组采用自制平喘膏配合场效应治疗仪治疗;西医给予沐舒坦、沙丁胺醇气雾剂治疗。两组患儿共治疗3个疗程后对比疗效。结果:治疗后中医组CD4+及CD4+/CD8+较治疗前均明显降低(P<0.01),CD8+比例上升,IgE水平明显降低(P<0.01)。中医组治疗后CD4+、CD4+/CD8+及IgE 3项指标与西医组比较,差异有统计学意义(P<0.01);中医组总有效率为89.74%,高于西医组总有效率72.50%(P<0.05);治疗后随访1年,中医组哮喘复发次数明显低于西医组(P<0.01)。结论:中医治疗儿童哮喘可有效纠正患儿体内T淋巴细胞亚群比例紊乱,降低介导过敏反应的IgE水平,可更好地减轻哮喘减少复发率。
Objective: To observe the clinical efficacy of traditional Chinese medicine and western medicine in the treatment of childhood asthma (remission). Methods: A total of 79 children with asthma remission were randomly divided into TCM group and WM group. Chinese medicine group using homemade asthma cream with field effect treatment instrument treatment; Western medicine given mucosolvan, salbutamol aerosol treatment. Two groups of children were treated after 3 courses of contrast efficacy. Results: The levels of CD4 + and CD4 + / CD8 + in TCM group were significantly lower than those before treatment (P <0.01). The proportion of CD8 + increased and the level of IgE decreased significantly (P <0.01). The total effective rate of TCM group was 89.74%, which was higher than that of Western medicine group’s total effective rate 72.50% (P <0.01) <0.05). One year after treatment, the number of asthma relapse in TCM group was significantly lower than that in Western medicine group (P <0.01). Conclusion: Chinese medicine treatment of childhood asthma can effectively correct the imbalance of T lymphocyte subsets in children and reduce the level of IgE that mediates anaphylaxis, which can reduce the recurrence rate of asthma better.