遗传性球形红细胞增多症合并血管性假血友病(附一个家族的调查)

• 作 者: 陈淑蓉 王振义 陈竺 支立民 蔡敬仁
• 机 构: 上海第二医学院附属瑞金医院内科血液组,上海第二医学院附属瑞金医院内科血液组,上海第二医学院附属瑞金医院内科血液组,上海第二医学院附属瑞金医院内科血液组,上海第二医学院附属瑞金医院内科血液组
• 出 处: 上海第二医学院学报
• 发表日期: 1983年03期
• 关键词: 血管性假血友病 血友病甲 先证者 尿色 家族 家系调查 球形红细胞 面色苍白 出生后 巩膜黄染

遗传性球形红细胞增多症(HS)是较常见的一种遗传性溶血性贫血,(1-3)血管性假血友病(VWD)其发生率仪次于血友病甲的遗传性出血性病病,但二病合并现象文献上尚未见报导,我院最近遇到一例,并作了家系调查,兹介绍如下。先证者滔××,女,20岁,浙江乐清人,住院号256205,患者出生后不久即发现皮肤发黄,面色苍白。近二年来时感乏力、头晕、眼花、耳呜、尿色如浓茶。

Hereditary spherocytosis (HS) is a more common form of hereditary hemolytic anemia, (1-3) von Willebrand disease (VWD), whose incidence is second to hereditary hemorrhagic disease in hemophilia A However, the literature on the phenomenon of the second disease has not been reported, our hospital recently encountered a case, and made a pedigree investigation, it is introduced as follows. The proband Tao XX, female, 20 years old, Yueqing, Zhejiang, inpatient number 256205, the patient was found shortly after birth skin yellow, pale. The past two years, lack of sense of time, dizziness, vertigo, tinnitus, urine color such as strong tea.