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为研究 β-七皂甙钠对减轻面部美容术后水肿和促进消肿 ,自 1996年 1月至 1997年 12月 ,我们将 40例行头面部皮肤提紧术的病人随机分为两组 ,一组术后用 β-七叶皂甙钠治疗水肿 ;另一组未行任何消肿治疗作为对照组。在头面部设计了 3条测量线作为检测肿胀程度的指标 ,在术前、术后第 3、5、7d分别记录测量数据 ,并进行统计学处理 ,结果显示 :β-七叶皂甙钠治疗组术后水肿程度较轻 ,消肿迅速 ,与对照组相比有显著差异 (P<0 .0 5 ) ,而且 ,用药 5 d比用药 3d对肿胀消退的程度有高度显著差异 (P<0 .0 1) ,再续用药 2 d,即术后用药 7d与用药 5 d对比 ,进一步消肿作用轻微。 2 0例治疗病人在住院期间及术后半年随访 ,均未发现明显的毒副作用。本研究证实了 β-七叶皂甙钠对减轻面部美容术后水肿及促进消肿有较明显的作用 ,并对其作用机理进行了讨论
In order to study the effect of β-saponin sodium on alleviating facial cosmetic postoperative edema and promoting swelling, from January 1996 to December 1997, we randomly divided 40 patients with face facial skin tightening surgery into two groups Group after treatment with β-aescinate treatment of edema; the other group without any swelling treatment as a control group. Three measuring lines were designed on the head and face as an index to detect the degree of swelling. Measurement data were recorded before and after surgery on the 3rd, 5th and 7th day respectively and the results were analyzed. The results showed that β-aescinate treatment group Postoperative edema was mild, swollen rapidly, compared with the control group was significantly different (P <0. 05), and, 5 d medication than the medication on the degree of swelling subsided highly significant difference (P <0. 0 1), continued medication 2 d, 7d after administration compared with medication 5d, further swelling was mild. Twenty cases of patients treated during hospitalization and six months after follow-up, did not find any significant side effects. This study confirmed that β-aescinate sodium to reduce facial cosmetic edema and promote swelling have a more obvious role, and its mechanism of action were discussed