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作者等对31例消化性溃疡给予1个月疗程的甲氰咪胍,治疗前及疗程结束后对其胃液检测pH和进行细菌学研究。病例和方法:对31例十二指肠溃疡(18例)和良性胃溃疡(13例)患者,用消毒胃镜吸取第一次胃液留作胃液标本。以后给予甲氰咪胍200mg每日三次及400mg临睡时口服。1个月疗程结束后,患者于上午7时服最后一片药,3~4小时后进行胃镜复查,并收集第二次胃液标本。每份标本立即用玻璃电极测pH,并作细菌学检查。用标准方法作需氧菌和厌氧菌培养及计数。细菌总数及各类细菌计算用log_(10)细菌数/ml胃液
The authors treated 31 patients with peptic ulcer for one month with cimetidine. Before treatment and after the end of treatment, the gastric juice was tested for pH and bacteriological study. Cases and Methods: 31 patients with duodenal ulcer (18 cases) and benign gastric ulcer (13 cases) were treated with sterile gastroscope to take the first gastric juice as gastric juice specimens. Cimetidine 200mg given after three times daily and 400mg orally when going to sleep. At the end of the first month of treatment, the patient took the last dose at 7:00 a.m., endoscopy was performed 3-4 hours later, and a second gastric juice sample was collected. Each specimen was immediately tested for pH with a glass electrode and subjected to bacteriological examination. Using standard methods for aerobic and anaerobic culture and counting. Bacterial count and various types of bacteria with log_ (10) bacteria / ml gastric juice