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目的：探讨自身免疫在女性外阴营养不良发生中的作用。方法：采用常规病理方法H．E染色，光镜观察，对病例进行病理分型。采用冰冻切片，直接免疫荧光法，荧光显微镜进行观察。并以健康人外阴组织为抗原（即在-20℃恒冷冰冻切片），用间接免疫荧光法，荧光显微镜观察，测病人血清中抗健康人正常外阴组织的抗体。结果：50例病员中27例局部有免疫球蛋白或C3沉积，11例血清中具有抗健康人外阴组织抗体，9例两项检测均为阳性。主要发生于表皮和真皮。并且与病情轻重具有一定关系。结论：在女性外阴营养不良的发病过程中自身免疫起着某种主导性作用。
Objective: To explore the role of autoimmunity in the occurrence of female vulvar dystrophy. Methods: Using conventional pathology method H. E staining, light microscopy, the pathological type of cases. Frozen sections, direct immunofluorescence, fluorescence microscopy were observed. Antibody of normal human vulvar tissue in normal human was detected by indirect immunofluorescence and fluorescence microscopy with normal human genital tissue as antigen (ie frozen frozen section at -20 ℃). Results: Of the 50 cases, 27 cases had immunoglobulin or C3 deposition locally, 11 cases had anti-healthy vulvar tissue antibody, and 9 cases both were positive. Occurs mainly in the epidermis and dermis. And with the severity of a certain relationship. Conclusions: Autoimmunity plays a dominant role in the pathogenesis of female vulvar dystrophy.