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由原发性肾病综合征(PNS)引起的急性肾功能衰竭(ARF)临床罕见,作者报告发生率为2.1%,分析了 ARF 与 PNS 在临床上的关系,阐明其临床病理表现,探讨其发病机理。PNS 患者420例,其中9例发生 ARF,根据其发生情况及预后分为两组:A组6例,为先有初发及复发的 PNS,以后发生 ARF,且 ARF 是可逆的;6例中男女各3例,年龄58.3±9.3岁,由 PNS 到发生ARF 的时间为12±10个月。B 组3例,为同时发生PNS 和 ARF,后来发生慢性肾衰(CRF);3例中男2,女1例,年龄50.3±7.1岁,PNS 和 ARF 同时发生。两组间年龄、性别、血压、尿蛋白量、血清白蛋白水平、钠滤过分数(FENa)、最初肾功能及并发
Acute nephrotic failure (ARF) caused by primary nephrotic syndrome (PNS) is clinically rare. The reported incidence of ARF was 2.1%. The clinical relationship between ARF and PNS was analyzed to clarify the clinical and pathological manifestations of ARF. mechanism. There were 420 cases of PNS patients, of which 9 cases were ARF, divided into two groups according to their occurrence and prognosis: A group of 6 cases, PNS first and recurrent, ARF later, and ARF was reversible; 6 cases There were 3 males and 3 females, aged 58.3 ± 9.3 years. The time from PNS to ARF was 12 ± 10 months. In group B, 3 cases were both PNS and ARF, followed by chronic renal failure (CRF); 3 males, 2 females and 1 females, aged 50.3 ± 7.1 years, PNS and ARF occurred simultaneously. Age, gender, blood pressure, urinary protein levels, serum albumin levels, FENa, primary renal function, and concurrent