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2型糖尿病的病理生理学特征是肝脏、脂肪组织和骨骼肌对胰岛素的抵抗以及胰岛 β细胞功能异常。这些异常因素的综合作用导致了慢性高血糖和严重的糖尿病急慢性并发症。胰岛素抵抗是导致 2型糖尿病的重要病因之一。胰岛素抵抗是指机体对一定量的胰岛素的生物学反应低于正常水平
The pathophysiological features of type 2 diabetes are resistance of the liver, adipose tissue, and skeletal muscle to insulin as well as dysfunction of islet beta cells. The combination of these abnormalities leads to chronic hyperglycemia and severe acute and chronic complications of diabetes. Insulin resistance is one of the important causes of type 2 diabetes. Insulin resistance refers to the body’s biological response to a certain amount of insulin below normal levels