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深入研究重要脏器血栓栓塞的发病机制和临床防治,对提高人类健康水平、生活质量以及降低该病的发病率、病死率有重要的现实意义。 1.研究内容:本项目采用40余种先进的血栓与止血的检测指标,对10种1332例重要的血栓栓塞性疾病(1019例正常对照)进行了全面、系统和动态的检测,并对检测项目进行了优化组合用于血栓病的诊断;利用先进的分子生物学技术,在基因水平上对血栓病的发病机制进行研究。具体研究内容包括:对重要脏器和其他血栓病进行优化组合的检测和全面、系统的研究;提出建立血栓前状态的筛选试验,
In-depth study of the pathogenesis of major organ thromboembolism and clinical prevention and control, to improve human health, quality of life and reduce the incidence of the disease, mortality has important practical significance. 1. Research Content: The project used more than 40 kinds of advanced detection indexes of thrombosis and hemostasis, conducted a comprehensive, systematic and dynamic examination of 10 kinds of 1332 important thromboembolic diseases (1019 normal controls) The project was optimized for the diagnosis of thrombosis; the use of advanced molecular biology techniques to study the pathogenesis of thrombosis at the genetic level. The specific research contents include: the optimal combination of important organs and other thrombosis detection and comprehensive and systematic study; put forward the establishment of pre-thrombotic state screening test,