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造血干细胞受损是再生障碍性贫血的主要发病原因之一,给患者补充一定量的造血干细胞可促进机体造血组织的重建,利用红细胞生成素作用下的体外培养法、动物体内扩散盒培养法和放射性核素测定技术,对胎肝造血细胞的生理特性进行系统研究,证明胎肝中含有丰富的增殖能力旺盛的造血细胞。选用4～5个月用水囊引产的新鲜胎肝310个,治疗再生障碍性贫血100多例,有效率达67%,其中自身胎肝输注者9例,有效率达100%,取得了良好的效果。
Hematopoietic stem cell damage is one of the main causes of aplastic anemia, to patients with a certain amount of added hematopoietic stem cells can promote the reconstruction of the body’s hematopoietic tissue, the use of erythropoietin in vitro culture method, the proliferation of animal in vivo culture and Radionuclide determination technology, the physiological characteristics of fetal liver hematopoietic cells were systematically studied to prove that fetal liver is rich in proliferative capacity of hematopoietic cells. Select 4 to 5 months with water sac induction of new fetal liver 310, treatment of aplastic anemia more than 100 cases, the effective rate of 67%, of which 9 cases of their own fetal liver transfusion, the effective rate of 100%, and achieved good Effect.