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新型抗高血压药物哌唑嗪,为α-肾上腺受体阻断剂,是一种结构全新的血管扩张药。化学上和目前所有的降压药品结构完全不同,是喹唑酮的衍生物。该药由美国辉瑞公司发明,于1976年首先用于临床。目前国内已有厂家生产。临床证明,哌唑嗪有显著的降压效果,不仅章低站位血压,也降低臥位血压。轻度和部分中度高血压病人可单独使用,中度和重度高血压病人可配用利尿药如β一肾上腺受体阻断剂、心得安等。能取得满意的疗效。哌唑嗪和其它降压药品相比,具有下列优点:(1)哌唑嗪和肼苯哒嗪等其它血管扩张剂相比,很少会引起心动过速,亦不增加肾素的分泌,也没有头痛、颜面潮红的副作用。
Prazosin, a new antihypertensive drug, is an α-adrenergic receptor blocker and is a brand new vasodilator. Chemical and all the current antihypertensive drugs completely different structure, is a derivative of quinazolinone. The drug invented by the United States Pfizer, first used in clinical in 1976. At present, there are manufacturers in China. Clinically proven, prazosin has a significant antihypertensive effect, not only chapter lower station blood pressure, but also lower supine blood pressure. Mild and some moderate hypertensive patients can be used alone, moderate and severe hypertension patients can be equipped with diuretics such as beta adrenergic receptor blockers, propranolol and so on. Can achieve satisfactory results. Prazosin compared with other antihypertensive drugs, has the following advantages: (1) prazosin and hydralazine and other vasodilators, rarely cause tachycardia, nor increase the secretion of renin, There is no headache, facial flushing side effects.