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目的:观察右美沙芬和左旋延胡索治疗干咳的临床疗效。方法:对63例病人进行随机分组盲法试验,右美沙芬组22例,剂量为15mg1天3次;左旋延胡索组20例,剂量为30mg1天3次;对照组21例,给予安慰剂,1片1天3次。疗程均为3天。结果:镇咳明显有效率:右美沙芬组为91%,左旋延胡索组为75%,对照组为53%。3组比较疗效有显著性差异(P<0.005~0.05),不良反应少。结论:说明右美沙芬和左旋延胡索均可用于干咳的治疗。
Objective: To observe the clinical efficacy of dextromethorphan and levo-corydalis in the treatment of dry cough. Methods: Sixty-three patients were randomly divided into blinded trial, dextromethorphan group (n = 22), nimodipine (15 mg once daily for three days), levosulfan group (n = 20) 3 times a day. Treatment are 3 days. Results: Antitussive was effective in 91% of dextromethorphan, 75% of levosulfan and 53% of control. The efficacy of the three groups was significantly different (P <0.005 ~ 0.05), less adverse reactions. Conclusion: Dextromethorphan and levocerane can be used to treat dry cough.