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目的对综合ICU患者多药耐药菌(MDR)感染情况进行分析,为MDR的预防和控制提供数据支持。方法取自2009年9月-2012年3月在医院综合ICU住院的298例患者送检标本1 965份进行分析,找出培养阳性的病原菌,筛选出MDR,并分析MDR的类型、感染部位分布等,所有数据采用SPSS 19.0进行分析。结果 1 965份标本共分离出病原菌746株,其中MDR 584株占78.3%,排前3位的MDR为鲍氏不动杆菌、肺炎克雷伯菌、铜绿假单胞菌,分别占32.0%、30.5%、12.8%;MDR感染部位分布以呼吸道、血液、泌尿道最多分别占48.5%、9.6%、3.9%;属于MDR医院感染的有306株,占52.4%。结论 MDR感染多由于医院感染而引起,因此应加强医院感染的管理,制定切实可行的管理制度,降低MDR感染的发生。
Objective To analyze the infection status of multidrug-resistant bacteria (MDR) in comprehensive ICU patients and provide data support for the prevention and control of MDR. Methods A total of 1 965 samples from 298 patients hospitalized in the hospital integrated ICU from September 2009 to March 2012 were analyzed to find out the positive pathogens, to screen for MDR, and to analyze the type of MDR and the distribution of infection sites. Etc. All data was analyzed using SPSS 19.0. Results A total of 746 pathogenic bacteria were isolated from 1,965 specimens, of which MDR 584 accounted for 78.3%. The top three MDRs were Acinetobacter baumannii, Klebsiella pneumoniae, and Pseudomonas aeruginosa, accounting for 32.0%, respectively. 30.5%, 12.8%; MDR infection site distribution of the respiratory tract, blood, urinary tract accounted for 48.5%, 9.6%, 3.9%; 306 strains of MDR hospital infection, accounting for 52.4%. Conclusion Most of MDR infections are caused by nosocomial infections. Therefore, the management of nosocomial infections should be strengthened, and a practical management system should be established to reduce the incidence of MDR infections.