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目的:了解机械通气患儿的静息能量消耗情况，分析其与人体测量学指标(身高、体质量、体质量指数)和血清蛋白学指标(前白蛋白、白蛋白、转铁蛋白、视黄醇结合蛋白)的相关性。方法:以2015年8月至2016年4月入住首都医科大学附属北京儿童医院儿童重症监护病房(PICU)的机械通气患儿为研究对象。入选标准：(1)小儿危重病例评分60 mL。在患儿接受机械通气的15～24 h采用美国麦加菲Med Graphic公司CCM/D能量代谢测定系统测量患儿静息能量消耗情况、德国Famed Zywier重症监护床自带体质量秤称量体质量、统一量床或米尺测量身高、全自动生化分析仪及放射免疫扩散法测定白蛋白、前白蛋白、转铁蛋白、视黄醇结合蛋白。采用SPSS 20.0软件进行n Pearson直线分析相关性。n 结果:共有68例患儿纳入研究，其中男36例，女32例，体质量(22.34±14.89) kg；身高(122.23±14.89) cm。静息能量消耗水平(784.63±278.25) kcal(1 kcal＝4.185 kJ)，每公斤体质量静息能量消耗(48.80±31.26) kcal。人体测量学指标中，静息能量消耗与身高、体质量均呈显著正相关(n r＝0.764、0.734，均n P60 mL.Resting energy expenditure was determined by US Med Graphic Company CCM/D energy metabolism test system.German Famed Zywier intensive care bed with weight scale weighing, uniform measuring bed or meter measuring height, automatic biochemical analyzer and radioimmunoassay was adopted for the determination of albumin, pre-albumin, transferrin, retinol binding protein.SPSS 20.0 software was applied for carrying outn Pearson line analysis correlation.n Results:A total of 68 children were included in the study, including 36 males and 32 females, body weight (22.34±14.89) kg, height (122.23±14.89) cm, resting energy consumption (784.63±278.25) kcal(1 kcal=4.185 kJ), and resting energy consumption per kilogram of body weight (48.80±31.26) kcal.In anthropometric indicators, resting energy expenditure was significantly positively correlated with height, body weight (n r=0.764, 0.734, all n P<0.05), a low positive correlation with body mass index(n r=0.396, n P<0.05). In serum proteomics, resting energy expenditure was negatively correlated with pre-albumin, transferrin (n r=-0.318, -0.282, all n P<0.05), and a moderate negative correlation with retinol protein (n r=-0.505, n P0.05).n Conclusions:The height, weight and serum proteomics of children with mechanical ventilation may affect resting energy expenditure.