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自从溶组织内阿米巴(Eh)能在无菌条件下人工培养(Diamond,1968),并以无菌培养物制取抗原(Thompsom等,1968)以来,近年关于阿米巴病的免疫学研究有了明显进展。 Eh虽然是单细胞动物,但它的抗原组成相当复杂。比如,用双向免疫电泳检测无菌Eh提取物发现,HT-31株有32个抗原组分,HK-9株为20个(Chang等,1979)。但是关于其中含有的保护性抗原的定性和定量,尚未完全清楚。关于人体对Eh的天然抵抗力,所知甚少。近来体外试验发现,将Eh滋养体与不
Immunology of amoebiasis has been reported since the E. histolytica (Eh) can be artificially cultured under aseptic conditions (Diamond, 1968) and antigens in sterile culture (Thompsom et al., 1968) Research has made significant progress. Although Eh is a single-celled animal, its antigen composition is quite complex. For example, using two-dimensional immunoelectrophoresis to detect sterile Eh extracts, 32 antigenic components were found in HT-31 and 20 in HK-9 (Chang et al., 1979). However, the qualitative and quantitative analysis of the protective antigens contained in them is not yet fully understood. Little is known about the body’s natural resistance to Eh. Recently in vitro experiments found that Eh trophozoites and not