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目的：追踪观察新生儿咽部巨细胞病毒（ＣＭＶ）感染状况，进一步分析感染对其生长发育的影响。方法：采用聚合酶链反应（ＰＣＲ）和病毒分离方法检测４２例新生儿咽部分泌物中ＣＭＶ感染状况。结果：新生儿咽部ＣＭＶ感染率为１６．７％（７／４２），７例咽部ＣＭＶ阳性者母亲宫颈分泌物或外周血ＣＭＶＤＮＡ均阳性。宫颈或外周血ＣＭＶＤＮＡ阳性者其新生儿咽部感染的危险性为４３．７％（７／１６），自然分娩和剖宫产者新生儿咽部ＣＭＶ感染率分别为１２．５％（２／１６）和１９．２％（２／１６），二者无显著差异。结论：孕妇ＣＭＶ感染可通过宫内和产道传播给胎儿，剖宫产不能防止新生儿咽部感染。
Objective: To observe the neonatal pharyngitis virus (CMV) infection status and further analyze the impact of infection on its growth and development. Methods: Polymerase chain reaction (PCR) and virus isolation were used to detect CMV infection in 42 neonates with pharyngeal secretions. Results: Neonatal pharyngeal CMV infection rate was 16.7% (7/42), 7 cases of pharyngeal CMV positive mothers cervical secretions or peripheral blood CMVDNA were positive. The risk of neoplasm infection was 43.7% (7/16) in CMVDNA positive cervical or peripheral blood, and 12.5% (2/8) in nasopharyngeal spontaneous delivery and cesarean section, respectively 16) and 19.2% (2/16), no significant difference between the two. Conclusion: CMV infection in pregnant women can be transmitted to the fetus through intrauterine and birth canal. Caesarean section can not prevent neonatal pharyngeal infection.