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目的对高血压并发冠心病患者应用氨氯地平阿托伐他汀钙片的临床疗效展开观察与探究。方法 90例高血压并发冠心病患者,随机分为对照组与观察组,各45例。对照组患者给予阿托伐他汀钙片治疗,观察组则应用氨氯地平阿托伐他汀钙片治疗。统计并对比两组患者的临床治疗效果及安全性。结果经治疗,观察组患者的血压改善总有效率为97.8%,心电图改善总有效率为95.6%,显著高于对照组的82.2%与77.8%,差异具有统计学意义(P<0.05)。对照组与观察组患者不良反应发生率均为6.7%,比较差异无统计学意义(P>0.05)。结论通过对高血压合并冠心病患者应用氨氯地平阿托伐他汀钙片进行治疗,具有明显的降压作用,可有效改善患者的心肌缺血情况,疗效安全可靠,值得临床推广应用。
Objective To investigate the clinical efficacy of amlodipine atorvastatin in hypertensive patients with coronary heart disease. Methods 90 patients with hypertension and coronary heart disease were randomly divided into control group and observation group, 45 cases in each. Patients in the control group were given atorvastatin calcium tablets and amlodipine atorvastatin calcium tablets in the observation group. Statistics and comparison of two groups of patients with clinical efficacy and safety. Results After treatment, the total effective rate of the observation group was 97.8%, the total effective rate of ECG improvement was 95.6%, significantly higher than that of the control group 82.2% and 77.8%, the difference was statistically significant (P <0.05). Adverse reactions in control group and observation group were 6.7%, the difference was not statistically significant (P> 0.05). Conclusion The application of amlodipine atorvastatin calcium tablets in hypertensive patients with coronary heart disease has obvious antihypertensive effect, which can effectively improve myocardial ischemia in patients with coronary artery disease. The curative effect is safe and reliable, which is worthy of clinical application.