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目的:观察基质层角膜营养不良患者行角膜穿透移植术后的远期疗效。方法:对22例22眼基质层角膜营养不良患者行角膜穿透移植术进行治疗,并对其远期疗效进行分析。结果:随访时间2～8年,22只术良中有21眼角膜植片均为透明(95.4%);视力>0.3者14眼(63.3%,脱残率)。结论:通过2～8年(平均为5.8年)的随访,并未见移植片的周边部发生基质层角膜营养不良的混浊现象,而且术后免疫排斥反应发生率低,可以证实角膜穿透性移植术是治疗基质层角膜营养不良的有效手术方法。
Objective: To observe the long-term efficacy of corneal penetrating surgery in patients with corneal dystrophy. Methods: Twenty-two patients with 22 corneal dystrophies were treated by corneal penetrating surgery and their long-term efficacy was analyzed. Results: The follow-up time ranged from 2 to 8 years. Among the 22 cases, 21 eyes were transparent (95.4%) and 14 eyes (63.3%, visual acuity). CONCLUSION: Corneal malnutrition and opacity in the periphery of the graft were not observed after 2 to 8 years (averaged 5.8 years) of follow-up, and the incidence of postoperative immunologic rejection was low, confirming corneal penetration Transplantation is an effective surgical treatment of corneal dystrophy.