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萘羟心安(nadolol)为一种新开发的长效β受体阻滞剂,本品对原发性高血压、心绞痛和快速型心律失常均有疗效,且具有一日投药一次即能保持稳定的疗效,对心肌收缩力抑制作用少及肾功能影响轻等特点。86年初,日本制药株式会社邀请有关医药学专家对萘羟心安的动物试验及临床应用效果进行评价,现摘要介绍如下: 一、动物试验表明萘羟心安较心得安(Inderal)疗效佳:日本制药株式会社药理研究所所长门河敏明氏,对萘羟心安的药理作用进行研究,该氏用犬作实验,观察本品异丙基肾上腺素诱发的心动过速及舒张压降低的抑制作用,结果本品的最大抑制率与心得安相等,但作用持续时间为心得安的5倍
Naphthol (nadolol) is a newly developed long-acting beta-blocker, this product is effective in patients with essential hypertension, angina pectoris and tachyarrhythmia, and has the ability to maintain stability once administered once a day Efficacy, less inhibition of myocardial contractility and renal function and other characteristics of light. In early 2006, Nippon Pharmaceutical Co., Ltd. invited medical experts to evaluate the effects of naphthalene and oxycodone in animal experiments and clinical applications. The summary is as follows: 1. Animal experiments show that NAFAR is more effective than Inderal: Pharmacological Institute of Japan, Kanebo Min-ming, pharmacological effects of naphthalene oxytocin study, the dogs for experiments to observe the product isoproterenol-induced tachycardia and decreased diastolic blood pressure inhibition, Results The maximum inhibitory rate of this product is equal to that of propranolol, but the duration of action is 5 times higher than that of propranolol