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癌症的早期发现对于提高疗效极为重要。用目前的诊查方法,半数以上的癌症直到晚期才能诊断出来,如果能早期查出,据估计,90%的癌症可以治愈,而现在仅35%能治。因此许多学者都在探求早期诊断癌症的简单的生化和免疫学方法。癌症早期生化改变的研究,开始进展十分缓慢,最近几年,由于发展了高敏感的精确的检测技术,研究进展大大加快,出现了一些有希望的生化指标。三年前,主要苗头是癌胚抗原(CEA)及甲胎蛋白(AFP)。它们是一类瘤胎抗原(Oncofetal antigens)和糖蛋白的原型,它们存在于肿瘤及胎儿组织中,在正常组织中不含或含量极少。目前在美国一些研究所,OEA 已常规用于某些肿瘤的
Early detection of cancer is extremely important for improving the efficacy. With current diagnostic methods, more than half of cancers can be diagnosed until late. If they can be detected early, it is estimated that 90% of cancers can be cured, but only 35% can be cured. Therefore, many scholars are exploring simple biochemical and immunological methods for the early diagnosis of cancer. Research on the early biochemical changes in cancer has progressed very slowly. In recent years, due to the development of highly sensitive and accurate detection techniques, research has accelerated greatly and some promising biochemical indicators have emerged. Three years ago, the main signs were carcinoembryonic antigen (CEA) and alpha-fetoprotein (AFP). They are the prototypes of a class of Oncofetal antigens and glycoproteins, which are present in tumors and fetal tissues and are absent or minimal in normal tissues. OAE has been routinely used for certain tumors in some U.S. institutes