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通常认为胰腺癌或壶腹周围恶性肿瘤侵犯肠系膜上－门静脉（SMPV）交汇处是胰十二指肠切除的禁忌证。本文作者试图确定胰十二指肠连同SMPV交汇处是否能安全地施行整块切除以及肿瘤侵犯SMPV交汇处是否与提示预后不佳的病理指标有关。数家医疗中心报告对胰头或壶腹部肿瘤施行胰十二指肠切除后腹膜后切缘阳牲率高。切缘阳性或切除不完全与肿瘤的早期复发有关，且与姑息疗法相比无生存的优越性。肿瘤粘附至SMPV侧或后壁常是胰十二指肠切除时肿瘤完全切除的唯一障碍。
It is generally considered that pancreatic cancer or periampullary malignant tumors invading the junction of the superior mesenteric-portal vein (SMPV) is a contraindication for pancreatoduodenectomy. The authors sought to determine whether pancreatic duodenal and SMPV junctions can safely perform whole resection and whether tumor invasion of SMPV junctions is associated with pathological indicators suggestive of poor prognosis. Several medical centers reported that the rate of perioperative retroperitoneal excision of pancreatoduodenectomy for pancreatic or ampullary tumors is high. Positive margins or incomplete resection are associated with early recurrence of the tumor and have no survival advantage over palliative care. Tumor adhesion to the SMPV side or posterior wall is often the only obstacle to complete tumor resection during pancreatoduodenectomy.