论文部分内容阅读
目的:回顾性研究我院儿先天性心脏病围手术期预防性应用抗菌药方案,比较两组患者住院时间、术后感染率、住院费用、抗菌药费用等方面的差别,探讨围手术期抗茵药的选择。方法:选取2)10年1～6月行先天性心脏病手术病历341份,按预防性使用抗菌药品种分为头孢替安组(272例)和头孢曲松组(69例),对观测指标进行统计学处理及数据分析。结果:两组患者的抗菌药预防使用时间、抗菌药日均费用、抗菌药总费用等三项指标差异显著(P<0.05);头孢曲松组较头孢替安组抗菌药使用时间缩短约0.5 d,日均费用及抗菌药总费用分别节省约41元和360元。结论:两组患者术后感染率差异无统计学意义,但头孢曲松组在经济学方面更有优势,可以有效降低医疗费用,减轻患者经济负担。
OBJECTIVE: To retrospectively study the perioperative prophylactic use of antibacterials in children with congenital heart disease in our hospital and to compare the differences in hospitalization time, postoperative infection rate, hospitalization expense and antimicrobial cost between the two groups, The choice of medicine. Methods: Two hundred and seventy-four patients with congenital heart disease underwent surgery from January to June in 2006. The patients were divided into cefotiam group (n = 272) and ceftriaxone group (n = 69) according to prophylactic use of antibacterials. Statistical analysis and data analysis. Results: There were significant differences (P <0.05) between the two groups in terms of the prophylactic use of antimicrobial agents, the average daily cost of antimicrobial drugs, and the total cost of antimicrobial drugs (P <0.05); the use time of antimicrobial drugs in ceftriaxone group was shortened by about 0.5 d, the average daily cost and the total cost of antibacterial drugs were saved about 41 yuan and 360 yuan. Conclusion: There was no significant difference in postoperative infection rate between the two groups. However, the ceftriaxone group had more advantages in economics and could effectively reduce the medical expenses and reduce the patients’ financial burden.