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目的:研究性早熟患儿的临床特征表现,总结分析导致发病的原因。方法:将我院收治的性早熟患儿30例作为研究对象,观察患儿的临床表现,分别进行一般特征检查、骨龄检查、超声检查、血清性激素指标检查、MRI检查,分析导致性早熟的影响因素。结果:女性患儿特征表现为乳房增大、乳房色素沉着、外阴分泌物增多、阴毛早现、阴道出血;男性患儿特征表现为身高增长过快、阴茎增大、阴毛早现、乳房肿大。导致患儿性早熟的原因包括环境因素、饮食因素、药物因素、社会心理因素等。结论:引发儿童性早熟的因素较多,需要通过临床、影像学、实验室检查及时确诊。尤其要关注农村婴幼儿的生活和饮食,增强家长的疾病认知,促进儿童健康成长。
Objective: To study the clinical features of children with precocious puberty and to summarize the causes of the disease. Methods: Thirty patients with precocious puberty admitted to our hospital were selected as the research object. The clinical manifestations of the children were observed. The general characteristics, bone age, ultrasound, serum hormone and MRI were examined to analyze the effect of precocious puberty factor. Results: The characteristics of women with breast enlargement, breast pigmentation, increased genital secretions, pubic hair early appearance, vaginal bleeding; male children characterized by height growth too fast, penis enlargement, pubic hair early, breast enlargement . Causes of precocious puberty in children include environmental factors, dietary factors, drug factors, social and psychological factors. Conclusion: There are many factors that cause precocious puberty in children and need to be diagnosed in time through clinical, imaging and laboratory tests. In particular, we should pay attention to the life and diet of infants and young children in rural areas, enhance parents’ cognition of diseases, and promote the healthy growth of children.