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标题化合物8—一种新的手性催化剂,通过丙二酸酯法及酶解拆分合成(s)—3—(2—氯苯基〕丙氨酸甲酯,进一步与溴苯发生格氏反应而成。
The title compound 8, a new chiral catalyst, was synthesized by the malonate method and enzymatic resolution of (S) -3- (2-chlorophenyl) alanine methyl ester and further Grignard Reaction.