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目的观察垂体后叶素联合654-2(山莨菪碱)治疗大咯血的治疗效果。方法将40例大咯血患者随机分为垂体后叶素联合654-2组(治疗组)19例和垂体后叶素组(对照组)21例,分别观察止血总有效率及止血起效时间。结果治疗组和对照组总有效率分别为89.47%和66.74%,止血起效时间治疗组明显短于对照组(7.7±1.5)h、(16.8±3.3)h,具有显著性差异(均为P<0.01)。结论联合应用垂体后叶素和654-2能明显提高大咯血的治疗效果。
Objective To observe the therapeutic effect of vasopressin combined with 654-2 (anisodamine) in the treatment of massive hemoptysis. Methods Forty patients with massive hemoptysis were randomly divided into pituitrin combined with 19 cases of 654-2 group (treatment group) and 21 cases of pituitrin group (control group). The total effective rate of hemostasis and the onset time of hemostasis were observed. Results The total effective rates of the treatment group and the control group were 89.47% and 66.74%, respectively, and those in the treatment group were significantly shorter than those in the control group (7.7 ± 1.5) h and (16.8 ± 3.3) h, respectively <0.01). Conclusion Combined application of pituitrin and 654-2 can significantly improve the treatment of massive hemoptysis.