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目的探讨老年 Guillain- Barre(GBS)综合征患者的临床特征及诊治途径。方法对 2 8例老年 GBS患者的临床资料进行分析。结果其临床特征与一般 GBS有所不同 :1前驱感染情况多种多样 ;2起病形式多种多样 ;3出现肢体远端肌萎缩者较多 ,部分患者出现肢体瘫痪不对称 ;4感觉障碍出现率高 ;5并发植物神经功能障碍者多 ;6合并颅神经损害多 ;7并发症、合并症多见 ,死亡率较高 ;8脑脊液有蛋白 -细胞分离现象者较少 ;9肌电图提示周围神经脱髓鞘性与轴索性病变同时存在。结论老年 GBS的临床特征与一般 GBS有所不同 ,早期误诊率较高 ,预后较差 ,值得临床重视。老年GBS的治疗有条件则可首选大剂量人血丙种球蛋白静滴 ,同时强调综合治疗 ,慎用激素
Objective To investigate the clinical features and diagnosis and treatment of elderly Guillain-Barre syndrome (GBS). Methods The clinical data of 28 elderly GBS patients were analyzed. Results The clinical features were different from those of GBS in general: 1 There were many cases of precursor infection, 2 varied forms of onset, 3 more limb atrophy, more limb paralysis in some patients, 4 sensory disturbances 5 high incidence of autonomic dysfunction were more; 6 with more cranial nerve damage; 7 complications, more common complications, higher mortality; 8 cerebrospinal fluid protein-cell separation were less; 9 EMG tips Peripheral nerve demyelination and axonal lesions exist. Conclusion The clinical features of elderly GBS are different from those of general GBS. The early misdiagnosis rate is high and the prognosis is poor, which deserves clinical attention. Treatment of elderly GBS may be the first choice of high-dose intravenous infusion of human gamma globulin, while emphasizing the comprehensive treatment, with caution hormone