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既往报道,丙型肝炎患者在干扰素(INF)治疗前后甲状腺功能障碍发生率和抗甲状腺抗体检出率均较高。某些资料证实,自身免疫性甲状腺炎患者中抗-HCV的检出率也较高,提示自身免疫性甲状腺炎可能由HCV所诱发。本文旨在明确慢性活动性丙型肝炎患者在INF治疗前后其自身免疫性甲状腺病的发生率是否有别于慢性活动性乙型肝炎患者。
Previous reports, hepatitis C patients with interferon (INF) before and after treatment of thyroid dysfunction and anti-thyroid antibody detection rate were high. Some data confirm that patients with autoimmune thyroiditis detection rate of anti-HCV is also high, suggesting that autoimmune thyroiditis may be induced by HCV. The purpose of this article is to determine whether the incidence of autoimmune thyroid disease in patients with chronic active hepatitis C before and after INF treatment is different from that of patients with chronic active hepatitis B.