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整合子 -基因匣子系统是近年在细菌中发现的天然克隆与表达系统 ,能捕获外来耐药基因 ,在整合子中形成多种耐药基因的组合、排列 ,是细菌耐药性播散的机制之一 ,对细菌及质粒基因组的进化具有重要意义。本文对整合子 -基因匣子系统的结构特征、基因匣子的移动性与表达、整合子的流行病学及超整合子等方面进行综述。
The integron-gene cassette system is a natural cloning and expression system found in bacteria in recent years. It can capture foreign drug resistance genes and form a combination and arrangement of multiple drug resistance genes in the integron, which is a mechanism of bacterial drug resistance dissemination One of the important bacterial and plasmid genome evolution. This review summarizes the structural features of the integron-gene cassette system, the mobility and expression of the gene cassettes, the epidemiology of the integron, and the super integron.