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目的:观察扶正抑瘤汤对晚期前列腺癌患者术后的疗效。方法:将行前列腺切除术的98例晚期前列腺癌患者随机数字法分为观察组和对照组,每组49例。对照组给予常规化疗治疗,观察组在常规化疗的基础上加用扶正抑瘤汤进行治疗。对两组局部病灶进展时间、远处转移时间、治疗前后细胞免疫功能指标水平及生存质量进行观察。结果:观察组局部病灶进展时间与远处转移时间均显著大于对照组,P<0.05;治疗后,观察组免疫功能指标CD3+、CD4+、CD4+/CD8+显著性增大,而CD8+显著性降低,且与对照组比较差异有统计学意义(P<0.05);治疗后,观察组生存质量评分为(69.83±1.69)分,显著高于对照组的(64.72±1.87)分,差异有统计学意义(P<0.05)。结论:扶正抑瘤汤可有效的延缓晚期前列腺癌术后患者局部病灶进展和转移,改善患者免疫功能和生存质量。
Objective: To observe the effect of Fuzheng Yiliu Decoction on postoperative patients with advanced prostate cancer. Methods: 98 patients with advanced prostate cancer undergoing radical prostatectomy were randomly divided into observation group and control group, with 49 cases in each group. The control group was given conventional chemotherapy, and the observation group was treated with Fuzheng Yiliu Decoction on the basis of conventional chemotherapy. The time to progression, the distant metastasis time, the level of cellular immune function and the quality of life before and after treatment were observed in two groups. Results: The progress time and distant metastasis time of local lesion in observation group were significantly larger than those in control group (P <0.05). After treatment, the immune function indexes of CD3 +, CD4 + and CD4 + / CD8 + in observation group were significantly increased, while CD8 + (P <0.05). After treatment, the quality of life in the observation group was (69.83 ± 1.69) points, which was significantly higher than that of the control group (64.72 ± 1.87), the difference was statistically significant (P < P <0.05). Conclusion: Fuzheng Yiliu Decoction can effectively delay the progression and metastasis of local lesion in patients with advanced prostate cancer and improve immune function and quality of life.