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结节病是一种原因不明的遍及全身的肉芽肿病,好发年龄20～40岁,病理特点为非干酪性类上皮细胞肉芽肿,几乎可以累及所有器官,特别是肺、周围淋巴结、眼、唾腺、肝、脾、皮肤和骨,很少累及心脏和神经系统。病程发展缓慢,可经多年而自然缓解,少数病例发展为弥漫性肺间质纤维化,而最后死于慢性肺原性心脏病,其病死率约4～10%。Kveim皮内试验在活动期常呈阳性,有助于区别其他肉芽
Sarcoidosis is an unidentified, granulomatous disease of the generalized origin that occurs predominantly in patients aged 20 to 40 years and is characterized by a non-parched, epithelioid granuloma that affects almost all organs, particularly the lungs, peripheral lymph nodes, and the eye , Salivary glands, liver, spleen, skin and bone, rarely involving the heart and nervous system. Slow course of development, after years of natural relief, a few cases of diffuse pulmonary fibrosis, and finally died of chronic pulmonary heart disease, the mortality rate of about 4 to 10%. The Kveim intradermal test is often positive during the active phase and helps distinguish the other granulation