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目的 研究巨细胞病毒和动脉粥样硬化的关系。方法 用PCR的方法检查巨细胞病毒在颈内动脉、冠状动脉和血中的分布情况 ,并与健康人作对照。结果 83 .3 %～ 86 .7%的动脉粥样硬化患者的动脉壁中存在巨细胞病毒 ,而非动脉粥样硬化患者的动脉壁中只有 6 .7%的标本中见巨细胞病毒 ,两者相差有高度显著性 (P <0 .0 1 ) ;在 42 .4%的动脉粥样硬化患者的血中查见巨细胞病毒 ,而对照组中只有 3 %查到巨细胞病毒 ,两者相差有高度显著性 (P <0 .0 1 )。结论 巨细胞病毒在动脉粥样硬化和动脉粥样硬化性脑梗死的病理过程中起着重要的作用
Objective To study the relationship between cytomegalovirus and atherosclerosis. Methods The distribution of cytomegalovirus (CMV) in the internal carotid artery, coronary artery and blood was examined by PCR and compared with healthy controls. Results Eighty-three percent to 86.7% of patients with atherosclerosis had cytomegalovirus in the arterial wall, while only 6.7% of the arterial wall in non-atherosclerotic patients had cytomegalovirus. Two Were significantly different (P <0.01); CMV was detected in 42.4% of patients with atherosclerotic blood and only 3% of patients in the control group were found cytomegalovirus, both The difference was highly significant (P <0.01). Conclusion Cytomegalovirus plays an important role in the pathogenesis of atherosclerosis and atherosclerotic cerebral infarction