Elevated expression of Gsα in intrahepatic cholangiocarcinoma associates with poor prognosis

• 作 者: Xiao-Yue Cao Hong-Jie Ji Yong-
• 机 构: LaboratoryofPathology,KeyLaboratoryofTransplantEngineeringandImmunology,DepartmentofLiverSurgery&
• 出 处: 国际肝胆胰疾病杂志：英文版
• 发表日期: 2017年6期
• 关键词: Gsα INTRAHEPATIC CHOLANGIOCARCINOMA IMMUNOHISTOCHEMISTRY PROGNOSIS
• 基金项目: Funding: This study is supported by grants from the NationalNatural Science Foundation of China (81472303), Applied andFundamental Research Project of Sichuan Province (2017JY0029)and Science and Tech

BACKGROUND: The stimulatory G protein α subunit (Gsα)plays important roles in diverse cell processes including tumorigenesis.Activating mutations in Gsα gene (GNAS) have been reported to be associated with poor prognosis in various human carcinomas. Furth