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目的 探讨正常及高碘摄入与儿童智力发育水平的关系。方法 根据江苏省丰县、沛县和铜山县 13个乡 (镇 )居民饮用水碘含量的检测结果 ,将其分 6个组 :水碘 <10 0 (A) ,10 0～ (B) ,30 0～ (C) ,5 0 0～ (D) ,70 0～ (E)和≥90 0 μg/L(F)。共选择 8～ 15岁学生 2 0 13名对其身高、体重、智商、尿碘水平进行测量 ,对 6个组的结果进行比较分析。结果 11岁以上年龄组 ,高碘的D组 (10 5 5 ) ,E组 (10 5 2 )和F组 (10 2 3)学生的平均智商显著低于正常的A组(10 8 9) (P <0 0 1) ;智商与水碘含量 (β =- 0 80 3)、尿碘含量呈负相关 (β =- 0 5 4 6 )。 11岁以下年龄组 ,F组学生的智商也显著低于A组学生。结论 过高碘摄入会影响儿童的智力发育 ,最高允许的碘浓度 ,水碘为 30 0 μg/L或尿碘80 0 μg/L。
Objective To investigate the relationship between normal and high iodine intake and children’s mental development. Methods According to the detection results of iodine in drinking water of 13 townships (towns) in Fengxian County, Peixian County and Tongshan County of Jiangsu Province, this study divided into six groups: water iodine <10 0 (A), 10 0 B, 30 0 ~ (C), 5 0 0 ~ (D), 70 0 ~ (E) and ≥ 90 0 μg / L (F). A total of 20 to 13-year-old students were selected to measure their height, weight, IQ and urinary iodine. The results of six groups were compared and analyzed. Results The average IQ of students aged 11 and older with high iodine in group D (1055), group E (1052) and group F (1023) was significantly lower than that in normal group A (1089) ( P <0.01). IQ was negatively correlated with water iodine (β = - 0 80 3) and urinary iodine (β = - 0 546). The age group under 11 years old, F group of students IQ was significantly lower than the A group of students. Conclusions Excessive iodine intake affects the intellectual development of children with the highest allowable iodine concentration of 30 0 μg / L for water iodine and 80 0 μg / L for urinary iodine.