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近年来许多国家加紧研究有关抗白喉、破伤风和百日咳的联合疫苗中各个成份最适宜的剂量问题,以期获得这些抗原可能的最小含量和减少副作用而不降低其效应的疫苗。本文检核了免疫法质量的条件下由最小剂量的百日咳、白喉和破伤风组成联合疫苗免疫原的性质及其引致的反应。作者等对5个地区自3个月至4岁应当进行抗白喉、破伤风和百日咳免疫接种的儿童,按常规的方法给予联合疫苗:免疫法——每间隔一月注射一
In recent years, many countries have stepped up research on the most appropriate dose of each component of the combination vaccine against diphtheria, tetanus and pertussis in order to obtain the smallest possible amounts of these antigens and reduce their side effects without reducing their effectiveness. This article examines the nature and the resulting responses of the combination vaccine immunogens produced by minimal doses of whooping cough, diphtheria and tetanus under the conditions of immunological quality. The authors, among others, immunized children immunized against diphtheria, tetanus and pertussis in three districts from 3 months to 4 years of age in combination with the usual regimen: Immunization - one injection every other month