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本文报道了用IFAT和ELISA方法对马来丝虫病基本消灭后期人群微丝蚴率由1990年的0.72%(9/1284)降至1994年的0.08%(1/1182);血清学检测,1990、1991、1994年IFAT阳性率分别为26.92%、20.19%和8.96%,ELISA则分别为23.50%、30.70%和14.20%,均呈下降趋势。微丝蚴血症者及原微丝蚴血症者同年检测,抗体阳性率及水平均明显高于正常人;人群抗体阳性随年龄增长而增加,10岁以下组儿童最低。两种方法应用比较,结果的符合率为70.9~84.6%,不符者中呈互补性;对个体多次检测的结果仍有波动。表明两者均可作为丝虫病后期流行病学监测方法。
In this paper, the population microfilariae rate of late stage of elimination of malayian filariasis was reduced from 0.72% (9/1284) in 1990 to 0.08% (1/1182) in 1994 by IFAT and ELISA. Serological tests showed that the positive rates of IFAT in 1990, 1991, and 1994 were 26.92%, 20.19% and 8.96%, respectively, while those in ELISA were 23.50%, 30.70% and 14.20% Showing a downward trend. Microfilariae and former microfilaremia were detected in the same year, the positive rate and level of antibody were significantly higher than normal; antibody positive group increased with age, the lowest in children under 10 years of age. The application of the two methods, the results of the coincidence rate of 70.9 to 84.6%, inconsistent with were complementary; the results of individual tests still fluctuate. Indicating that both can be used as epidemiological monitoring methods of late filariasis.