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黏膜相关淋巴组织淋巴瘤(mucosa associated lymphoidtissue lymphoma,MALT-ML)最初由Isaacson和Wright于1983年提出[1],是指在长期抗原刺激下,结外黏膜上皮相关组织产生免疫应答及局部炎症,并在后天形成的淋巴组织当中促使免疫反应性淋巴细胞增生,产生异常克隆而导致的非霍奇金淋巴瘤(NHL),大多为低度恶性,预后较好,但部分可向高度恶性转变。好发于胃[2],口腔颌面部者以涎腺多见,称为涎腺黏膜相关淋巴组织淋巴瘤。
Mucosa-associated lymphoid tissue lymphoma (MALT-ML) was originally proposed by Isaacson and Wright in 1983 [1] and refers to the immune response and local inflammation of extranodal mucosal epithelial tissue under long-term antigen stimulation, And in the formation of lymphoid tissue to promote immunoreactive lymphocyte proliferation, resulting in abnormal clonal non-Hodgkin’s lymphoma (NHL), mostly low-grade, the prognosis is good, but some can be highly malignant transformation. Occur in the stomach [2], oral and maxillofacial salivary gland more common, known as salivary gland mucosa-associated lymphoid tissue lymphoma.