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目的 观察下壁急性心肌梗死早期应用卡维地洛的耐受性。方法 34例急性下壁心肌梗死在入院早期(3.6±4.2)d应用卡维地洛,共用(25±14.2)d。结果 服药后病人心率[(67±8)次/min]比服药前[(75±8)次/min]明显减慢(P<0.001),收缩压明显减低[111±13mmHg对118±15mmHg](P<0.01)。心肌耗氧指标心率×血压乘积明显降低(P<0.01),均未出现严重缓慢心律失常或低血压,仅1例心功能Ⅲ级患者心功能恶化,其余患者心功能均有改善。结论 下壁急性心肌梗死早期应用卡维地洛耐受性良好。
Objective To observe the early application of carvedilol in inferior wall acute myocardial infarction. Methods Carvedilol was given to 34 patients with acute inferior myocardial infarction (3.6 ± 4.2) d during the first hospital admission, sharing (25 ± 14.2) days. Results After treatment, the heart rate of patients was significantly lower than that of the control group [(67 ± 8) min / min vs [75 ± 8] min / min] and the systolic blood pressure was significantly reduced [111 ± 13 mmHg vs 118 ± 15 mmHg] (P <0.01). Myocardial oxygen consumption index heart rate × product of blood pressure was significantly lower (P <0.01), no severe slow arrhythmia or hypotension, only 1 patient with cardiac function Ⅲ grade deteriorated heart function, other patients have improved cardiac function. Conclusion The early application of carvedilol in inferior wall acute myocardial infarction is well tolerated.