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目的评价无创正压通气(NIPPV)对慢性阻塞性肺疾病(COPD)急性加重期并发呼吸衰竭的治疗价值。方法选择接受NIPPV的COPD患者28例,以同期同样标准COPD患者32例作为对照组(常规治疗组),动态观察两组患者通气、氧合、心率、呼吸频率等改善情况。结果NIPPV治疗组同期血气、心率、呼吸频率等较对照组明显改善(P均<0.05)。NIPPV治疗组插管率、病死率、住院时间较常规治疗组(对照组)均明显降低(P<0.05),临床有效率较对照组明显升高(P<0.05)。结论NIPPV治疗COPD急性加重期伴呼吸衰竭疗效确切、安全,减轻症状,减少气管插管率,促进患者康复。
Objective To evaluate the value of noninvasive positive pressure ventilation (NIPPV) in the treatment of respiratory failure complicated by acute exacerbation of chronic obstructive pulmonary disease (COPD). Methods Twenty-eight COPD patients receiving NIPPV were enrolled in this study. Twenty-two patients with the same standard COPD during the same period were selected as control group (conventional treatment group). The improvement of ventilation, oxygenation, heart rate and respiratory rate were observed dynamically. Results Compared with the control group, the blood gas, heart rate and respiratory rate of NIPPV treatment group were significantly improved over the same period (all P <0.05). NIPPV treatment group intubation rate, mortality and hospital stay than the conventional treatment group (control group) were significantly lower (P <0.05), the clinical effective rate was significantly higher than the control group (P <0.05). Conclusions NIPPV treatment of acute exacerbation of COPD with respiratory failure is effective, safe, relieve symptoms, reduce tracheal intubation rate, and promote patient rehabilitation.