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目的:探讨手足口病37例临床分析。方法:对2007～2008年我院门诊和住院部收治的37例手足口病的临床资料进行了回顾性分析,即对患者的性别、年龄、首发症状、皮疹形态、发展过程、部位,并发症辅助检查结果、疗效及死亡原因等进行分析。结果:37例患儿中11例(29.7%)发生在人员聚集单位,62.2%的皮疹与口腔粘膜疱疹同时出现,先为玫瑰色红斑或斑丘疹,24h后转为疱疹,好发于手掌、足底、指趾的屈面等表皮厚而容易受到摩擦的部位,在口腔、手掌同时出现皮疹者为23例,口腔、手掌、足底同时出现者为14例(37.8%;血常规检查:白细胞总数正常18例(48.4%),白细胞总数升高5例(1 3.0%),白细胞总数下降14例(37.8%);淋巴细胞增高占23例(62.1 6%),中性粒细胞较低5例(1 3.51%),中性粒细胞增高8例(21.62%)。心电图检查:心电图异常11例,窦性心动过速8例(21.6%),心肌炎2例(8.11%)。肝功异常即单项转氨酶增高3例(8.1%)。胸片检查,支气管炎4例(10.8%),支气管肺炎3例(8.1%),合并扁桃体炎5例(16%),脑电图广泛异常1例(4%)。结论:本病系由病毒感染性疾病,呈自限性,经抗病毒及对症治疗,支持疗法后预后良好,很少有并发症,但重症患者可合并心肌炎及脑膜炎危及生命。预防本病传播流行的关键是及时发现并隔离患儿。
Objective: To investigate the clinical analysis of 37 cases of hand, foot and mouth disease. Methods: The clinical data of 37 cases of hand, foot and mouth disease admitted to outpatient department and inpatient department of our hospital from 2007 to 2008 were analyzed retrospectively. The patients’ gender, age, initial symptom, rash morphology, development process, location and complications Auxiliary examination results, efficacy and cause of death were analyzed. Results: Of the 37 children, 11 cases (29.7%) occurred in staff gathering units. 62.2% of the rashes appeared in conjunction with oral herpes simplex at first. Foot, toe flexor and other epidermal thick and prone to friction sites, in the mouth, palms at the same time there were 23 cases of rash, oral, palms and foot at the same time were 14 cases (37.8%; blood test: The total number of white blood cells was normal in 18 cases (48.4%), the total number of white blood cells increased in 5 cases (130%), the total number of white blood cells decreased in 14 cases (37.8%), the lymphocyte increased in 23 cases (62.1%), neutrophils There were 5 cases (1551%) and 8 cases (21.62%) with increased neutrophil.Electrocardiogram: 11 cases of abnormal electrocardiogram, 8 cases of sinus tachycardia (21.6%) and 2 cases of myocarditis (8.11% Abnormalities were 3 cases (8.1%) of single transaminase increased, chest X-ray examination, bronchitis in 4 cases (10.8%), bronchopneumonia in 3 cases (8.1%) and tonsillitis in 5 cases (16% Cases (4%) .Conclusion: The disease is caused by viral infectious disease, self-limiting, after anti-virus and symptomatic treatment, the prognosis is good with supportive therapy, there are few complications, but severe patients may be combined with myocarditis Life-threatening meningitis. The key to preventing the spread of this disease epidemic is to detect and isolate children.