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报道对４３例有不同转归的癫痫病人和１１例正常对照组进行静注安定致脑电活动β功率改变和脑脊液（ＣＳＦ）中强啡肽Ａ１—１３（ＤｙｎＡ１—１３）、亮脑啡肽（Ｌ—ＥＫ）、生长抑素（ＳＳ）变化的前瞻性研究结果。发现复发病人静注安定后脑电活动β功率增加的量比未复发组和对照组低（Ｐ＜０．０５），而ＣＳＦ中ＤｙｎＡ１—１３、Ｌ—ＥＫ则高于未复发组和对照组（Ｐ＜０．０５），两者之间呈负相关（ｒ＝－０．７８，ｒ＝－０．６９，Ｐ＜０．０５），ＳＳ在三组间无显著区别，提示神经递质的改变可能是安定所致脑电β功率改变的物质基础。
Reported in 43 cases of different outcomes in patients with epilepsy and 11 cases of normal control group of intravenous transesophageal amygdala β-induced changes in electrical activity and cerebrospinal fluid (CSF) in the dynorphin A1-13 (DynA1-13), bright enkephalin (L-EK), somatostatin (SS) changes in the results of a prospective study. It was found that the increase of β power in patients with relapsed after intravenous diazepam was lower than that in the non-relapsed group and the control group (P <0.05), while the levels of DynA1-13 and L-EK in CSF were higher than those in the non-relapsed group and the control group (R = -0.78, r = -0.69, P <0.05). There was no significant difference in SS between the three groups, suggesting that neurotransmitter The change may be the material basis for the change in brain electrical β power due to stability.