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目的探讨糖尿病早期肾损伤诊断中,测定尿微量白蛋白价值。方法选取糖尿病患者40例,均为我院2015年6月~2016年6月收治,设为观察组,同期取健康体检者40例,设为对照组,均对24h尿液留取,对尿微量白蛋白水平进行测定。结果观察组所抽取的糖尿病患者28例为阳性,为70%阳性率;对照组健康体检者未检出阳性病例;测定24h尿微量白蛋白检测值,观察组为(125.42±81.66)mg/L,明显高于对照组健康体检者(18.05±4.17)mg/L,对比具显著统计学差异(P<0.05)。观察组40例糖尿病患者,病程<1年3例,1年<10例<5年,<5年17例<10年,10例>10年,随病程延长,阳性率呈升高趋势,且尿微量白蛋白检测值也呈增高表现,均呈正相关性。结论针对临床收治的糖尿病病例,对尿微量白蛋白进行测定,可为诊断早期肾损伤提供有力参考依据,为一项重要的监测肾损伤的指标。
Objective To investigate the value of urine microalbumin in the diagnosis of early diabetic nephropathy. Methods Forty patients with diabetes mellitus were enrolled in our hospital from June 2015 to June 2016, and were enrolled as observation group. Forty healthy subjects were selected as control group, Microalbumin levels were measured. Results In the observation group, 28 cases of diabetic patients were positive, which was 70% positive rate. In the control group, no positive cases were detected in the healthy subjects. The measured value of 24h urine microalbumin was (125.42 ± 81.66) mg / L , Which was significantly higher than that of the control group (18.05 ± 4.17) mg / L, with significant difference (P <0.05). 40 cases of diabetic patients in the observation group, the course of disease <1 year in 3 cases, 1 year <10 cases <5 years, <5 years 17 cases <10 years, 10 cases> 10 years, with the duration of the disease, the positive rate showed an upward trend Urine microalbumin test also showed increased performance, were positively correlated. Conclusion For the clinical cases of diabetes mellitus, the determination of urinary albumin can provide a powerful reference for the diagnosis of early renal injury, which is an important indicator of renal injury.