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目前此病很少见,但仍有偶发的病例。在绿色蔬菜、水果及动物蛋白不易得到的偏僻地区,此病仍在流行。在非洲及亚洲的一些国家,以玉米或高粱为主食的地区,此病仍呈地方性的流行。病原和病因:糙皮病是由于细胞内缺少烟酸所造成的。烟酸的重要性主要是它有形成辅酶一烟酰胺腺嘌呤二核苷酸(NAD)及磷酸烟酰胺腺嘌呤二核苷酸(NADP)的作用。这些酶含有烟酰胺腺嘌呤、D-磷酸核糖及磷酸,是氢的载体,因而对细胞
The current disease is rare, but there are still occasional cases. The disease is still prevalent in remote areas where green vegetables, fruits and animal protein are not readily available. In some countries in Africa and Asia, where maize or sorghum are the staple food, the disease is still endemic. Pathogens and causes: pellagra is due to the lack of niacin in the cells caused. The importance of nicotinic acid is mainly its role in the formation of coenzyme-nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucleotide (NADP). These enzymes contain nicotinamide adenine, D-phosphate ribose and phosphoric acid, which are carriers of hydrogen and therefore act on the cells