论文部分内容阅读
目的了解浙江省金华市2009-2010年甲型H1N1流感流行病学和临床相关特征,为甲型H1N1流感防治工作提供参考依据。方法收集金华市2009-2010年甲型H1N1流感监测资料和现场流行病学调查资料,使用描述流行病学方法分析甲型H1N1流感确诊病例的“人群、地区、时间”分布,以及重症(危重)病例既往慢病史、并发症、转归等相关临床特征。结果 2009-2010年金华市共报告甲型H1N1流感确诊病例687例,累计报告发病率为13.5/10万,其中轻症579例,重(危重)病例108例,死亡6例,分别占84.3%、15.7%和0.9%。病例多集中在经济较发达、人口流动较频繁的县(市、区),发病人群以儿童、青少年、学生为主。在不同年龄组的重症(危重)病例中,危症病情发生率不同(χ2=7.718,df=2,P<0.05);既往有慢病史有31人,占28.7%,与既往无慢病史者相比,有慢病史者较易发生危症病情(χ2=6.651,P<0.05);肺炎、呼吸衰竭、急性呼吸窘迫综合征(ARDS)等为重病(危重)病例主要并发症。结论 2009-2010年金华市甲型H1N1流感以青少年儿童、轻型感染为多见;甲型H1N1流感病例临床严重性存在年龄分布差异,有慢性疾病史是危重病例发生的危险因素,肺炎、呼吸衰竭、ARDS为甲型H1N1流感主要并发症。
Objective To understand the epidemiology and clinical characteristics of Influenza A (H1N1) from 2009 to 2010 in Jinhua City, Zhejiang Province, and to provide reference for prevention and control of Influenza A (H1N1). Methods The epidemiological data of H1N1 influenza from 2009 to 2010 in Jinhua City were collected and the “population, area, time” distribution of confirmed cases of influenza A (H1N1) were analyzed by using descriptive epidemiological method. Critically ill) past history of chronic disease, complications, outcome and other related clinical features. Results A total of 687 cases of H1N1 influenza were reported in Jinhua City from 2009 to 2010, with a cumulative incidence of 13.5 / 100,000. Among them, 579 were mild, 108 were severe and 6 were dead, accounting for 84.3% , 15.7% and 0.9% respectively. Cases are mostly concentrated in counties (cities, districts) where the economy is more developed and the population flow more frequently. The incidence population is mainly children, adolescents and students. In the severe (critical) cases of different age groups, the incidence of the disease was different (χ2 = 7.718, df = 2, P <0.05); there were 31 people with chronic disease history in the past, accounting for 28.7% Patients with chronic diseases were more likely to have the disease (χ2 = 6.651, P <0.05). Pneumonia, respiratory failure and acute respiratory distress syndrome (ARDS) were the main complications in severe cases. Conclusion The H1N1 influenza in Jinhua City was more common among young children and light-weight infections in 2009-2010. The clinical severity of Influenza A (H1N1) patients was different in age distribution. Chronic disease history was the risk factor for critically ill patients. Pneumonia, respiratory failure , ARDS is the main complication of influenza A (H1N1).