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目的:探讨丹红注射液对急性脑梗死患者的临床疗效及其对血清超敏C反应蛋白(Hs-CRP)、肿瘤坏死因子-α(TNF-α)、神经元特异性烯醇化酶(NSE)指标的影响。方法:选取2015年3月—2016年12月间收治的急性脑梗死患者80例,采用随机分组法将其分为观察组(n=40)和对照组(n=40);对照组患者给予复方丹参注射液治疗,观察组患者给予丹红注射液治疗,比较两组患者治疗后的总有效率和治疗前后Hs-CRP、TNF-α、NSE指标的变化情况。结果:观察组患者治疗后的总有效率为92.50%高于对照组为75.00%(P<0.05);观察组患者治疗后血清Hs-CRP、TNF-α、NSE测得值显著低于对照组(P<0.05)。结论:丹红注射液用于治疗急性脑梗死患者,有助于降低血清Hs-CRP、TNF-α和NSE水平,抑制炎症反应,改善神经功能缺损,疗效较为显著。
Objective: To investigate the clinical efficacy of Danhong injection in patients with acute cerebral infarction and its effects on serum Hs-CRP, TNF-α, NSE The impact of the indicator. Methods: Eighty patients with acute cerebral infarction who were admitted from March 2015 to December 2016 were selected and randomly divided into observation group (n = 40) and control group (n = 40). Patients in the control group Compound Danshen injection and observation group were treated with Danhong injection. The total effective rate and the changes of Hs-CRP, TNF-α and NSE before and after treatment were compared between the two groups. Results: The total effective rate after treatment in the observation group was 92.50%, which was significantly higher than that in the control group (75.00%, P <0.05). The Hs-CRP, TNF-α and NSE in the observation group were significantly lower than those in the control group (P <0.05). Conclusion: Danhong injection for the treatment of patients with acute cerebral infarction, help reduce serum levels of Hs-CRP, TNF-α and NSE, inhibit the inflammatory response and improve neurological deficit, the effect is more significant.