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自从英国医生Withering于1785年首先用洋地黄治疗水肿,至今已有200年历史。近些年,除了从许多植物中提取强心甙之外,还通过对已知强心甙或甙元的改造,半合成了具有一定优点的新强心甙。如β-甲基地戈辛、乙酰毒毛旋花子甙元等。本文根据强心甙药理学理论,讨论临床应用中的一些实际问题。叙述一些看法及体会。一、强心甙在治疗心力衰竭中的重要地位及其生效机理治疗心力衰竭应该是综合性的治疗措施,如卧床
It has been 200 years since the British doctor Withering first treated digitalis with edema in 1785. In recent years, in addition to extracting cardiac glycosides from many plants, new cardiac glycosides with certain advantages have also been semi-synthesized through the modification of known cardiac glycosides or aglycones. Such as β-methyl Geoxin, acetyl poison hair Cyanide aglycone and so on. This article based on pharmacological theory of cardiac glycosides to discuss some practical problems in clinical applications. Describe some ideas and experiences. First, the importance of cardiac glycosides in the treatment of heart failure and its mechanism of effective treatment of heart failure should be a comprehensive treatment measures, such as bed rest